The current and future impact of osteoarthritis and rheumatoid arthritis on the economy, the NHS, families and individuals is revealed in a campaign from Arthritis Research UK. Continue reading
Common and modifiable factors that predict poor quality of life in people with ankylosing spondylitis have been highlighted in research from the University of Aberdeen. Continue reading
Arthritis Care will merge into Arthritis Research UK and work as one charity from October 2017. Continue reading
A new insight into the genetics of ankylosing spondylitis could aid future treatment of the disease, says research in the Proceedings of the National Academy of Sciences.
Experts are developing compounds that could allow the pain-relieving effects of ibuprofen to last longer, they report in Molecular Pharmaceutics. And the approach could also be used to deliver other drugs orally that currently can only be taken intravenously.
Metal-organic frameworks are compounds made of metal ions linked to organic ligands, for drug delivery. Active ingredients can be packed inside the metal organic frameworks. They are porous, and some dissolve in water so are good candidates for drug couriers.
The researchers loaded ibuprofen into metal organic frameworks. The compounds were found to reach the bloodstream (of mice) quickly and lasted for twice as long as ibuprofen salts, which are the active ingredient in liquid gel formulations.
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