Arthritis Care will merge into Arthritis Research UK and work as one charity from October 2017. Continue reading
A potential drug target for particle-driven diseases such as gout may be a focus of new treatments, a research team reports in the Journal of Leukocyte Biology. Continue reading
A diet known to reduce the risk of hypertension and cardiovascular disease may also lower the risk of gout, says research published in the British Medical Journal. Continue reading
Experts are developing compounds that could allow the pain-relieving effects of ibuprofen to last longer, they report in Molecular Pharmaceutics. And the approach could also be used to deliver other drugs orally that currently can only be taken intravenously.
Metal-organic frameworks are compounds made of metal ions linked to organic ligands, for drug delivery. Active ingredients can be packed inside the metal organic frameworks. They are porous, and some dissolve in water so are good candidates for drug couriers.
The researchers loaded ibuprofen into metal organic frameworks. The compounds were found to reach the bloodstream (of mice) quickly and lasted for twice as long as ibuprofen salts, which are the active ingredient in liquid gel formulations.
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The action of gut microorganisms on dietary fibres may reduce inflammation associated with gout, highlights research in the Journal of Leukocyte Biology.