Juvenile Arthritis

World’s first ibuprofen patch delivers pain relief directly through skin

ibuprofen, pain relief, patch, arthtitis digest magazineAn ibuprofen patch that delivers the drug directly through skin to exactly where it is needed at a consistent dose rate, has been invented in the UK. A team from the University of Warwick found a way to incorporate significant amounts of ibuprofen (up to 30% weight) into the polymer matrix that sticks the patch to the patient’s skin with the drug then being delivered at a steady rate over up to 12 hours. Continue reading

New childhood arthritis therapies recommended in draft NICE guidance

juvenile idiopathic arthritis, childhood arthritis, new drugs, new therapies, arthritis digest magazine A number of new juvenile idiopathic arthritis therapies have been provisionally recommended by the UK’s National Institute for Health and Care Excellence (NICE) for use within the NHS.

The final draft guidance says that abatacept (Orencia), adalimumab (Humira), etanercept (Enbrel) and tocilizumab (RoActemra) will be endorsed as an option for children and young people with arthritis. Continue reading

Discovery of a molecular switch to stop inflammation?

switch off inflammationA molecular switch – MYSM1 – may be able to suppress the overreaction of the immune system and could prevent inflammatory diseases experts claim in Immunity.

Although the immune system is vital for protection and healing, it can overreact causing chronic inflammatory diseases, such as rheumatoid arthritis. Continue reading

Genetic component of childhood arthritis is assessed along with other childhood-onset autoimmune diseases

juvenile idiopathic arthritis Scientists have calculated more precise measurements of heritability – the influence of genes – in nine autoimmune diseases that begin in childhood, they report in Nature Communications. It is hoped the research may strengthen the ability of healthcare professionals to predict a child’s risk for associated autoimmune diseases and lead to new treatments. Continue reading

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