Exercise improves physical function and reduces painkiller use in people with hip and knee osteoarthritis
Implementation of an exercise protocol was linked with improved physical function in people with knee and hip osteoarthritis, experts revealed at the Osteoarthritis Research Society International World Congress. Continue reading
Exercise and physical activity programmes are increasingly being promoted as a way of treating chronic pain conditions, but what does the evidence show? Continue reading
Experts are developing compounds that could allow the pain-relieving effects of ibuprofen to last longer, they report in Molecular Pharmaceutics. And the approach could also be used to deliver other drugs orally that currently can only be taken intravenously.
Metal-organic frameworks are compounds made of metal ions linked to organic ligands, for drug delivery. Active ingredients can be packed inside the metal organic frameworks. They are porous, and some dissolve in water so are good candidates for drug couriers.
The researchers loaded ibuprofen into metal organic frameworks. The compounds were found to reach the bloodstream (of mice) quickly and lasted for twice as long as ibuprofen salts, which are the active ingredient in liquid gel formulations.
For more in-depth features, interviews and information, subscribe to Arthritis Digest magazine, a popular title that’s published six times a year. Click here for the digital version or tel 0845 643 8470 to order your had copy. You’ll know what your doctor is talking about, what new drugs are in the pipeline and be up to date on helpful products.
People in England may be missing out on hip and knee surgery because of the way pain scoring tools are being used.
Data from the UK Orthopaedics Industry Group suggests that at least 10% of clinical commissioning groups (CCGs) across England are using unproven scoring tools to restrict access to orthopaedic surgery. Continue reading
Oral nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in the treatment of pain in fibromyalgia, despite being considered not to be effective. Continue reading