Most people with rheumatoid arthritis have life-altering pain daily or multiple times a week despite treatment – new survey
A survey has revealed that there is significant unmet need amongst people living with rheumatoid arthritis in terms of treatments and support. Continue reading
Newly identified cells help explain why women experience autoimmune disease more often than men, a team reports in the Journal of Clinical Investigation. Continue reading
Experts are developing compounds that could allow the pain-relieving effects of ibuprofen to last longer, they report in Molecular Pharmaceutics. And the approach could also be used to deliver other drugs orally that currently can only be taken intravenously.
Metal-organic frameworks are compounds made of metal ions linked to organic ligands, for drug delivery. Active ingredients can be packed inside the metal organic frameworks. They are porous, and some dissolve in water so are good candidates for drug couriers.
The researchers loaded ibuprofen into metal organic frameworks. The compounds were found to reach the bloodstream (of mice) quickly and lasted for twice as long as ibuprofen salts, which are the active ingredient in liquid gel formulations.
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People with rheumatoid arthritis have a higher risk of atherosclerosis, the build-up of fatty material inside the arteries, experts explain in Scientific Reports. Continue reading