The body clock and time of day impact on immune responses, researchers outline in Nature Communications, a finding that may help inform drug-targeting strategies to alleviate autoimmune disease. Continue reading
The pros and cons that drinking coffee has on health are widely reported in the media. Now a group of experts looking at the association between coffee intake and its influence on the immune system have reported some interesting findings in Autoimmunity Reviews. Continue reading
The current and future impact of osteoarthritis and rheumatoid arthritis on the economy, the NHS, families and individuals is revealed in a campaign from Arthritis Research UK. Continue reading
Arthritis Care will merge into Arthritis Research UK and work as one charity from October 2017. Continue reading
Experts are developing compounds that could allow the pain-relieving effects of ibuprofen to last longer, they report in Molecular Pharmaceutics. And the approach could also be used to deliver other drugs orally that currently can only be taken intravenously.
Metal-organic frameworks are compounds made of metal ions linked to organic ligands, for drug delivery. Active ingredients can be packed inside the metal organic frameworks. They are porous, and some dissolve in water so are good candidates for drug couriers.
The researchers loaded ibuprofen into metal organic frameworks. The compounds were found to reach the bloodstream (of mice) quickly and lasted for twice as long as ibuprofen salts, which are the active ingredient in liquid gel formulations.
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