Multiple corticosteroid injections do not seem to benefit arthritis knee pain
Osteoarthritis knee pain may not be reduced by multiple corticosteroid injections says a review of the evidence published in Rheumatology. And the injections may make the situation worse.
Minor adverse events were similar in both groups (treatment versus placebo). But one trial actually found that regular steroid injections every three months for two years caused greater cartilage loss compared with placebo injections.
Another found that multiple injections were associated with worsening of joint space narrowing and increased the risk of joint replacement.
“Multiple intra-articular corticosteroid injections are no better than placebo for osteoarthritis pain according to current evidence,” the teams says. “The preliminary finding of a detrimental effect on structural osteoarthritis progression warrants further investigation.”
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