Golimumab well tolerated in rheumatoid arthritis says data review
Golimumab, a biologic drug for people with rheumatoid arthritis, appears to be effective and well tolerated, according to a review of the evidence in the Journal of Clinical Medicine.
Golimumab is usually used alongside methotrexate and is given once a month by injection under the skin, usually into the thigh, tummy or upper arm (ie a subcutaneous injection). It comes as an injector pen or a syringe, to use at home
As well as phase 3 trials, real-world data is now being gathered about golimumab in action.
“It seems that golimumab in the subcutaneous form is an efficacious molecule with a good safety profile at the standard dosage scheme, but a 100mg subcutaneous dose is associated with a higher risk of opportunistic infections, lymphoma and demyelination,” the researchers say. “Furthermore, when compared to other tumor necrosis factor-α molecules, it is non-inferior, and, at some points, such as when it comes to immunogenicity and persistence of the drug, it has a better profile.
“In summary, golimumab is an effective, well-tolerated option for the treatment of rheumatoid arthritis, for both the clinician and patients who are seeking a convenient dosage scheme.”
Click here to read the original findings.
Arthritis Digest Magazine was selected by Feedspot as one of the Top 5 Arthritis Blogs on the internet in 2018.
For more in-depth features, interviews and information, subscribe to Arthritis Digest magazine, a popular title that’s published six times a year. Click here for the digital version or tel 0845 643 8470 to order your had copy. You’ll know what your doctor is talking about, what new drugs are in the pipeline and be up to date on helpful products.