Rheumatoid Arthritis
Could upadacitinib provide greater benefits than methotrexate? Results of a new trial are in…
A drug called upadacitinib may have better results than methotrexate, the most commonly used initial therapy for rheumatoid arthritis, according to a new trial in Arthritis & Rheumatology. Continue reading
Tiny scorpion-derived proteins deliver arthritis drugs to joints
A minute protein in scorpion venom that rapidly accumulates in joint cartilage has been linked with steroids to reverse arthritis inflammation in arthritis. The drugs concentrated in the joints, potentially avoiding the body-wide toxicities and infection risks caused by non-targeted treatment. Continue reading
Pain, distress and central sensitisation in arthritis
Most forms of arthritis are associated with pain and psychological distress in the form of depression and/or anxiety. It is a viscous circle as pain and depression are mutually exacerbating; both may continue even when joint involvement appears well controlled. Now a review of the evidence has found arthritis-related stress impacts the central nervous system and together with inflammatory changes may cause central sensitisation that can lead to chronic pain and distress. Continue reading
Intensive and early treatment of rheumatoid arthritis reduces fatigue experts advise
Early intensive treatment that combines methotrexate with prednisone can reduce the profound fatigue that impacts many people with rheumatoid arthritis.
The new research from Belgium recommends that even low-risk patients should be considered for early intensive treatment. Continue reading
Online consultations for people with chronic pain during lockdown
Conditions for people living with chronic pain have been exacerbated by the covid-19 pandemic but telemedicine may improve the situation, according to research from the University of Bath. Continue reading
