Grape seed extract resveratrol may reduce symptoms of knee osteoarthritis

Resveratrol, a polyphenol extract from grape seeds has anti-inflammatory properties, and new research has found that when given alongside a nonsteroidal anti-inflammatory drug it reduces symptoms of knee osteoarthritis, experts outline in the Journal of Medicinal Food.

A total of 110 men and women (45–75 years old) who had knee osteoarthritis were treated with 15mg meloxicam (NSAID) and either 500mg resveratrol or placebo every day for 90 days. Pain severity was evaluated at the beginning and at the end of treatment and levels of inflammation biomarkers were recorded.

People who had resveratrol in addition to the meloxicam had a greater decrease in pain and levels of the biochemical markers of inflammation were reduced compared with the placebo-treated group. The team concludes:

“These findings suggest that resveratrol may be an effective ‘add-on’ option with meloxicam in the treatment of patients with mild to moderate knee osteoarthritis.”

Click here to read the original research.

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