ArthritisDigest2013
Antidepressant – duloxetine – under spotlight for osteoarthritis knee pain
A drug called duloxetine is under scrutiny as a potential treatment for chronic osteoarthritis knee pain, explains research published in Therapeutic Advances in Musculoskeletal Disease.
Three trials were carried out which found that: Continue reading
Good news for fathers-to-be
Men with rheumatoid arthritis who take low doses of methotrexate may be reassured by new research that shows they have no increased risk of negative pregnancy outcome.
Methotrexate is associated with malformations in unborn children of women who take the drug. Published in Rheumatology, a study involving 113 pregnancies fathered by men who were treated with low-dose methotrexate around conception looked at incidence of major birth defects, spontaneous abortion, gestational age at delivery and birth weight. Continue reading
Fracture risk increases with high blood pressure
High blood pressure increases the risk of osteoporosis and fracture in women who have been through menopause, says research published in Osteoporosis International.
Scientists measured the bone mineral density and carried out interviews and X-rays on 1,032 men and 1,701 women aged at least 50 years. Continue reading
Breastfeeding lowers rheumatoid arthritis risk in women
Breastfeeding for a longer time is associated with a lower risk of rheumatoid arthritis, says research published in Rheumatology. And women who had breastfed are about half as likely to have rheumatoid arthritis compared to those who had never breastfed.
The study involved 7349 women in China aged at least 50 years. A questionnaire established that most women had at least one child, and of these, over 95% had breastfed for at least one month. Only 11% had used the contraceptive pill, and mostly for a short time. The average age of first pregnancy was 24 years and the average age of rheumatoid arthritis diagnosis was 47.5 years. Continue reading
Ustekinumab examined as ankylosing spondylitis treatment
A drug called ustekinumab (Stelara) has had promising results in the treatment of ankylosing spondylitis (AS) – a severe form of inflammatory back pain – according to a study published in the Annals of the Rheumatic Diseases.
The trial involved an injection of 90mg of the drug at the start of the trial, week four and week 16 in 20 people with active AS. Continue reading