Cannabinoids and rheumatic diseases – evidence review

As medical use of cannabis becomes more accepted around the world a better understanding of the medical and hazardous effects of this drug is imperative, experts report in Nature Reviews Rheumatology.

“Thus far, preliminary clinical trials have explored the effects of cannabis on rheumatoid arthritis, osteoarthritis and fibromyalgia,” the team explains in their review of the evidence. “Preliminary evidence has also found an association between the cannabinoid system and other rheumatic conditions, including systemic sclerosis and juvenile idiopathic arthritis.”

The potential medicinal effects of cannabis could be due to its influence on the immune system, as it may have an immunomodulatory effect on various immune cells including T cells, B cells and macrophages. The researchers conclude:

“The available evidence is not yet sufficient to support the recommendation of cannabinoid treatment for rheumatic diseases.”

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