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Juvenile Arthritis
Young people with arthritis choose treatments that “make life normal”
Young people with arthritis make treatment decisions based on how the treatment will affect their appearance, social life and physical and mental well-being, says new research. The small study, which will be presented at the British Society for Rheumatology’s conference Rheumatology 2014, suggests that young people are concerned about whether treatments could threaten their day-to-day life.
Inflammatory arthritis can need aggressive treatment including the use of biologic therapies. For young people, making these crucial treatment decisions comes at a difficult time in their personal and disease development. It is vital that the right decision is made because these decisions can have major consequences. Continue reading
Kids with juvenile idiopathic arthritis waiting too long for diagnosis
Over one-third of diagnoses of juvenile idiopathic arthritis are delayed – by up to two years after the onset of symptoms – by GPs or paediatricians, outlines a report from the National Rheumatoid Arthritis Society.
JIA is an inflammatory disease which causes chronic arthritis in children and young people and affects approximately 12,000 children (1 in 1000) under the age of 16 years. The severity of arthritis can vary from mild to extremely disabling and symptoms include stiff, painful and swollen joints. JIA is associated with other complications such as blindness which results from uncontrolled inflammation around the lens of the eye and can also significantly delay physical development in the very young, cause permanent joint damage and deformity and delay puberty. Continue reading
Stem cell generation breakthrough for older people
A new technique has been developed for harvesting stem cells from older people with arthritis undergoing hip replacement surgery, says research published in Stem Cells Translational Medicine.
The team from the University of New South Wales in Australia has found that that certain tissue usually discarded during routine hip replacements (periosteum-derived stem cells) may be a rich source of adult stem cells, which could then be used in various regenerative medicine applications. “Remarkable similarities” were found between them and commercial bone marrow stem cells. Continue reading
Zebrafish research sheds light on possible bone regeneration
Research into bone regeneration in zebrafish could one day form the basis of treatments for bone diseases, says research published in Cell Reports.
Two molecular pathways have been found that allow adult zebrafish to replace bones lost after fin amputation. One turns existing bone cells into a developmental stem cell-like state, helping them to grow and replace lost cells; the other encourages the newly-formed cells to turn back into functional, organised bone. Continue reading
Fresh approach needed for torn cartilage repair
Knee surgery to repair torn cartilage are no better than placebo ops, suggests research published in The New England Journal of Medicine.
The Finnish Degenerative Meniscal Lesion Study (FIDELITY) compared surgical treatment of degenerative meniscal tears to placebo surgery. Continue reading