Juvenile Arthritis
Study identifies human protein that triggers Juvenile Arthritis
A new study, led by researchers at Albert Einstein College of Medicine and the Children’s Hospital at Montefiore (CHAM), has found evidence that a human protein called transthyretin (TTR) causes an autoimmune reaction in the joints of Juvenile idiopathic arthritis patients. Continue reading
World’s first ibuprofen patch delivers pain relief directly through skin
An ibuprofen patch that delivers the drug directly through skin to exactly where it is needed at a consistent dose rate, has been invented in the UK. A team from the University of Warwick found a way to incorporate significant amounts of ibuprofen (up to 30% weight) into the polymer matrix that sticks the patch to the patient’s skin with the drug then being delivered at a steady rate over up to 12 hours. Continue reading
New childhood arthritis therapies recommended in draft NICE guidance
A number of new juvenile idiopathic arthritis therapies have been provisionally recommended by the UK’s National Institute for Health and Care Excellence (NICE) for use within the NHS.
The final draft guidance says that abatacept (Orencia), adalimumab (Humira), etanercept (Enbrel) and tocilizumab (RoActemra) will be endorsed as an option for children and young people with arthritis. Continue reading
Discovery of a molecular switch to stop inflammation?
A molecular switch – MYSM1 – may be able to suppress the overreaction of the immune system and could prevent inflammatory diseases experts claim in Immunity.
Although the immune system is vital for protection and healing, it can overreact causing chronic inflammatory diseases, such as rheumatoid arthritis. Continue reading
Genetic component of childhood arthritis is assessed along with other childhood-onset autoimmune diseases
Scientists have calculated more precise measurements of heritability – the influence of genes – in nine autoimmune diseases that begin in childhood, they report in Nature Communications. It is hoped the research may strengthen the ability of healthcare professionals to predict a child’s risk for associated autoimmune diseases and lead to new treatments. Continue reading
