Lupus

Lupus: puzzle begins to unravel… and 43 areas of DNA are involved

lupus, genetic, gene, DNA, treatment, arthritis digest magazineA total of 43 different areas of DNA contain genetic risk factors that increase the chance of developing systemic lupus erythematosus, scientists outline in Nature Genetics.

Lupus is a severe autoimmune disease that is more common than leukaemia and multiple sclerosis. Currently incurable, the disease affects about 24,700 people in the UK and is believed to be genetic in origin. Continue reading

Discovery of a molecular switch to stop inflammation?

switch off inflammationA molecular switch – MYSM1 – may be able to suppress the overreaction of the immune system and could prevent inflammatory diseases experts claim in Immunity.

Although the immune system is vital for protection and healing, it can overreact causing chronic inflammatory diseases, such as rheumatoid arthritis. Continue reading

Blood test will identify pregnant women with lupus who have low risk of adverse outcomes

lupus, pregnancy, baby, blood testPregnant women with systemic lupus erythematosus have a higher risk of adverse pregnancy outcomes but monitoring specific biomarkers in maternal blood during early pregnancy can successfully predict who is likely to have a normal pregnancy, experts explain in the American Journal of Obstetrics & Gynecology. The finding will allow healthcare professionals to identify and manage women at high risk early on and improve outcomes. Continue reading

Over 10% of US adults live in chronic pain says new analysis of data

chronic pain statistics arthritis digest magazineMost adults in the US have experienced some level of pain, from brief to more lasting (chronic) pain, and from relatively minor to more severe pain, say a new analysis of data from the 2012 National Health Interview Survey (NHIS). And an estimated 25.3 million adults (11.2%) experience chronic pain, ie pain every day for the preceding three months. Continue reading