Development of injection for osteoarthritis knee pain fast tracked in the US
A synthetic injection of trans-capsaicin for the treatment of pain linked with knee osteoarthritis has been given the green light for quick development in the US.
CNTX-4975 is injected directly at the site of joint pain to provide rapid and long-lasting pain relief for people with moderate-to-severe osteoarthritis knee pain.
People with osteoarthritis knee pain for whom previous pain relief hadn’t worked, found significant pain relief continuing beyond 24 weeks from a single 1mg injection of CNTX-4975. And they enjoyed improved knee stiffness and physical function during the trial. CNTX-4975 was well-tolerated too, having a safety profile similar to placebo.
“We look forward to building on the momentum of our CNTX-4975 program with the initiation of our phase 3 program in patients with moderate-to-severe knee osteoarthritis in the first quarter of 2018,” says Dr Randall Stevens from Centrexion Therapeutics, the company behind the drug.
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