Etanercept may be superior to methotrexate in psoriatic arthritis

Etanercept alone or in combination with methotrexate, seems to work better than methotrexate monotherapy in people with psoriatic arthritis, according to recent study findings in Arthritis and Rheumatology.

A total of 851 people with psoriatic arthritis (average age 48 years old) were recruited from 17 countries, and randomly selected to receive weekly doses of either oral methotrexate (20mg) plus placebo, etanercept (50mg) plus placebo or etanercept (50mg) plus oral methotrexate (20mg).

Etanercept monotherapy and combination therapy showed greater efficacy than methotrexate monotherapy in measures of disease activity and radiographic progression. And combining methotrexate and etanercept did not improve etanercept efficacy.

Click here to read the original research.

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