Glucosamine hydrochloride and chondroitin sulphate reduces pain and swelling of knee osteoarthritis says new study

Glucosamine hydrochloride chondroitin sulphate FLEXABLE Sustained Release Glucosamine tabletsCombining glucosamine hydrochloride (CS+GH) and chondroitin sulphate is an effective way to relieve pain in people with knee osteoarthritis, according to a new study in the Annals of the Rheumatic Diseases.
Experts compared CS+GH with the drug celecoxib (a non-steroidal anti-inflammatory drug [NSAID]) in 606 people who had knee osteoarthritis with moderate-to-severe pain. The participants were given the new combination or celecoxib for six months and were assessed for pain, function, effusion (release of fluid), stiffness and swelling.
Results showed that 79.7% of the people in the CS+GH group had reduced pain, as did 79.2% of those treated with celecoxib. Joint swelling reduction of more than 50% was reported in both groups, with a similar drop seen for effusion. Negative side effects were minimal and similar in both groups.
The researchers conclude that CS+GH has a comparable level of efficiency to celecoxib for treating knee osteoarthritis and represents a safe option for reducing pain stiffness, functional limitation and joint swelling/effusion.

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FLEXABLE Sustained Release Glucosamine tablets are formulated using an internationally patented polymer membrane permeation controlled technology that allows the glucosamine to be released slowly over an extended period of 12 hours. This ensures that glucosamine is at a steady concentration in the blood, enabling greater absorption and efficacy.
The active ingredient, glucosamine hydrochloride, is a compound found naturally in the body. It is made from glucose and the amino acid glutamine. Glucosamine is required to produce glycosaminoglycan, a molecule used in the formation and maintenance of joint cartilage, ligaments and tendons. The body’s ability to manufacture glucosamine declines with age resulting in degradation of cartilage.
ClockTaking FLEXABLE Sustained Release Glucosamine tablets as a nutritional supplement may help maintain cartilage by enhancing the body’s supply of glucosamine. FLEXABLE Sustained Release Glucosamine is designed to promote the synthesis of collagen which provides the natural cushion to cartilage. This may help support healthy joint movement and flexibility.

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