Marijuana’s potential for treating arthritis

A compound in marijuana – tetrahydrocannabinol (THC) – may be beneficial in treating those with autoimmune disorders, says research published in the Journal of Biological Chemistry.

The study from the University of South Carolina is the first to explore how tiny, yet powerful molecules called microRNAs are influenced by THC. MicroRNAs plan a vital role in gene expression; they act as brakes that target over 60% of gene expression. Being able to alter microRNA expression could hold the key to successful treatments for a whole host of autoimmune diseases, including arthritis.

Scientists involved in the current study identified 13 microRNAs that are highly altered by THC but the effect may be “a double-edged sword”. Its ability to suppress inflammation provides effective treatment against inflammatory and autoimmune diseases, but that very action may leave the body open and vulnerable to other diseases.

To read the original research visit http://www.jbc.org/content/early/2013/11/07/jbc.M113.503037.abstract?sid=7da5b2a0-9940-4ea3-90b4-eed1d9107a51.