Study suggests heart monitor implant has potential to save lives of people with systemic sclerosis

heart-1237254_1280 copyA heart monitor, no bigger than a packet of chewing gum, enables early detection and treatment of potentially fatal cardiac arrhythmias in people with system sclerosis (SSc).

The results of a pilot study were presented last month at the European League Against Rheumatism Annual Congress (EULAR 2016) and showed that use of any easy to insert heart monitor in people with SSc and no known heart disease enables early detection and treatment of cardiac arrhythmias. The findings support the need to identify SSc patients at risk of heart problems that would benefit from this implanted recorder.

SSc is an autoimmune rheumatic disease affecting multiple organs, including the heart. Damage to the heart as a direct consequence of SSc may involve the conduction system that controls the heartbeat, the heart muscle, heart valves and/or the external lining of the heart. Cardiac involvement is thought to be common in patients with SSC, although there are often no symptoms or signs.

Dr Lesley-Anne Bissell of the Musculoskeletal Biomedical Research Unit, at the University of Leeds says, “We know that cardiac involvement of SSc is associated with a very poor prognosis, accounting for between 14 – 55% of deaths among patients with SSc. Early diagnosis and treatment to reduce the risk of complications is therefore essential and crucial for a positive outcome.”

This heart monitor (also known as an implantable loop recorder) is a subcutaneous, single-lead, electrocardiographic (ECG) monitoring device used to diagnose heart rhythm abnormalities. It is capable of storing ECG data automatically in response to any significant change in heart rhythm, or in response to patient activation when symptoms are experienced. Its use is well established in cardiology practice.

The device, about the size of a pack of chewing gum, is typically inserted through a small cut to lie under the skin in the upper left chest. Electrodes that monitor the heart’s electrical activity are on the surface of the device, so there are no wires, and the device is enclosed in a protective case. The procedure is performed under local anaesthetic and takes 15-20 minutes.

In this pilot study, the heart monitor picked up a variety of heart rhythm abnormalities in more than half of the cohort of 19 SSc patients, including supraventricular ectopics, ventricular ectopics, ventricular tachycardia and complete heart block. Cardiac Magnetic Resonance imaging data available for 15 of these SSc patients showed markers of cardiac damage that significantly correlated with these heart rhythm abnormalities.

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