Pain, distress and central sensitisation in arthritis

central sensitisation, arthritis pain, arthritis depression, arthritis anxiety, arthritis digestMost forms of arthritis are associated with pain and psychological distress in the form of depression and/or anxiety. It is a viscous circle as pain and depression are mutually exacerbating; both may continue even when joint involvement appears well controlled. Now a review of the evidence has found arthritis-related stress impacts the central nervous system and together with inflammatory changes may cause central sensitisation that can lead to chronic pain and distress. Continue reading